milbemycin oxime used as a broad spectrum antiparasitic

milbemycin oxime (trade name interceptor, marketed by elanco) is a veterinary drug from the group of milbemycins, used as a broad spectrum antiparasitic. it is active against worms (anthelmintic) and mites (miticide).

mechanism of action
like avermectins, milbemycins are products of fermentation by streptomyces species. they have a similar mechanism of action, but a longer half-life than the avermectins. milbemycin oxime is produced by streptomyces hygroscopicus aureolacrimosus. it opens glutamate sensitive chloride channels in neurons and myocytes of invertebrates, leading to hyperpolarisation of these cells and blocking of signal transfer.

uses
milbemycin oxime is active against a broad

we are chemical manufacturer of 129496-10-2 from china.

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